NCOR2 anticorps

N° du produit ABIN5701136

L’anticorps Lapin Polyclonal anti-NCOR2 a été validé pour WB, ELISA et IF. Il convient pour détecter NCOR2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour NCOR2 anticorps (ABIN5701136)

Antigène: NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCOR2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-NCOR2 anticorps

Fonction: NCOR2 antibody

Immunogène: nuclear receptor co-repressor 2

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur NCOR2

Antigène: NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

Autre désignation: NCOR2

Sujet:

Synonyms: Nuclear receptor corepressor 2 (N-CoR2)|CTG repeat protein 26|SMAP270|Silencing mediator of retinoic acid and thyroid hormone receptor (SMRT)|T3 receptor-associating factor (TRAC)|Thyroid-, retinoic-acid-receptor-associated corepressor|NCOR2|CTG26

Background: Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center(GC) reactions, mainly through the control of the GC B-cells proliferation and survival.

Poids moléculaire: 180 kDa

ID gène: 9612

UniProt: Q9Y618

Pathways: Signalisation Notch, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha